IV Glutathione Therapy in EdmontonTruMed offers Edmonton IV Glutathione Treatments.Glutathione Background Glutathione is a tripeptide present in every cell of the human body Glutathione is thought to play crucial roles in the detoxification and antioxidant systems in cells. Glutathione is synthesized in nearly all cells in the body from glutamic acid, cysteine, and glycine with cysteine considered rate limiting. It serves as an important central nervous system antioxidant, clears free radicals including superoxide radicals, hydroxyl radicals, nitric oxide radicals and hydrogen peroxide. Glutathione helps maintain the body's cellular redox state and "low‐molecular‐weight" antioxidants such as Vitamin E and Vitamin C and is involved in maintenance of immune function. Even partial Glutathione depletion impairs immune function and increases susceptibility to a wide range of xenobiotics and oxidative damage. Low Glutathione levels are associated with increased risks of numerous diseases and our Naturopathic doctors always consider augmenting levels in patients with neurological disease. In Parkinson's disease glutathione is reduced by 40–50%. and this reduction is specific within the brain to the substantia nigra and correlates with disease severity and its related to mitochondrial complex I activity and dopaminergic function.
Patients with MS have substantially lower GSH concentrations than controls, and GSH was lower in progressive MS (PPMS and SPMS) compared with RRMS. Improving Glutathione status is certainly a goal for our Naturopaths in our MS patients as well as many other neurological diseases.
When glutathione is added to melanocytes or melanoma cell lines, the melanogenetic pathway is shifted from eumelanin towards pheomelanin formation. Our Experience Our Naturopaths have been proudly offering high dose Glutathione IV treatments since 2010 for Neurological health, Detoxification, Inflammation and Cosmetics. Glutathione IVs are remarkably well tolerated even when our Naturopathic Doctors are dosing it aggressively(5000-8000mg).
Intravenous Glutathione is administered fairly rapidly so it doesn't take a long time to have a strong treatment at our Edmonton clinic.
Dr Muradov in particular has seen good effect in treating acute exacerbations of MS with IV Glutathione.
IV Glutathione can be administered after our "Glut Pre-IV" - a multi-vitamin and mineral IV with emphasis on B5, Vitamin C and Selenium for improving Glutathione recycling. |
||
 |
High Dose IV Glutathione in Edmonton |
|
|
For cosmetic effect, our Naturopaths combine IV Glutathione with Intravenous Vitamin C. Our Naturopathic Doctors will often recommend oral Glutathione between IV treatments for maximum effect. |
||
|
Glutathione is the body's strongest anti-oxidant.
Interested in IV Glutathione Injections?Call us (780) 757-8378 |
||
|
Select Glutathione studies Fatty Liver Disease: A therapeutic effect of glutathione by oral administration in patients with Non Alcoholic Fatty Liver Disease. The 29 patients who were treated with 300mg of oral glutathione for 4 months showed a reduction in ALT levels as well as reductions in triglycerides and ferritin level (Honda 2009). Our Naturopaths often add Vitamin C and E supplementation which has been studied in NAFLD in part due to their Glutathione augmenting effects. Parkinson's Disease: 11 parkinson's patients received 1400mg intravenous glutathione and 10 received placebo administered three times a week for 4 weeks and a mild symptomatic benefit was seen. It was thought that in this study the total dose of Glutathione was too low. A 2017 study with intranasal glutathione also showed subtle effect (Hauser & Perlmutter 2009) Reported a 42% decline in Parkinson's disability with 600 mg glutathione administered intravenously twice daily for 30 days. The therapeutic effect was observed to last for 2 to 4 months (Sechi 1996). Our Naturopathic doctors have experience with Glutathione IV with Parkinson's and the effects are person dependant - some patients have rapid and profound effect whereas other patients the effects are subtle. Kidney Health: Twenty-one patients with reduced renal function who underwent coronary angiography were equally assigned to NAC or Glutathione 30 min (3000mg) before the procedure and it was found that intravenous Glutathione is more effective in preventing the oxidative stress to the kidneys than oral NAC (Saito 2011). Immune Function: A 6-month randomized, trial of oral Liposomal Glutathione (250 or 1,000 mg/day). At 6 months, mean GSH levels increased 30-35 % in erythrocytes, plasma and lymphocytes and 260 % in cheek cells in the high-dose group as well as a significant increase in NK cell cytotoxicity as Glutathione is needed in part for proper immune function (Richie Jr 2015). Our Naturopathic doctors often add 1-2 grams of Glutathione to our immune boosting IV treatments. Chemoprotection: Twenty patients suffering from advanced non small cell lung cancer or head- and neck cancer received cisplatin along with etoposide or 5-fluorouracil every 4 weeks, 11 of which were randomized to 5000mg of Glutathione given before cisplatin. The intensity of hematologic toxicity was significantly less pronounced in patients treated with Glutathione than in the control group and efficacy of chemotherapy was not affected (Schmidinger 2000). IV Glutathione can be done prior to patients receiving Platin based chemotherapy. An office visit would be needed so our Naturopaths can administer Glutathione prior to a hospital visit for chemotherapy. Skin Whitening: Sixty otherwise healthy medical students were randomized to receive either glutathione capsules, 500 mg/day in two divided doses, or placebo for 4 weeks. At 4 weeks, the melanin indices decreased consistently at all six sites in subjects who received glutathione (Arjinpathana 2012). Our Naturopathic doctors have substantial experience with IV Glutathione for cosmetic benefit. In our Edmonton patients we are often administering 5-10 grams of IV Vitamin C along with 2-5 grams of IV Glutathione. Glutathione FAQ How many Glutathione IVs do I need?The amount and frequency of Glutathione IV treatments depends on the condition. For instance, for skin health and cosmetic effect our Naturopaths often use 1-2 weekly Glutathione treatments for 4-8 weeks with oral Glutathione augmenting adjuncts. For neurological health, we may use Glutathione daily if the condition is acute like a MS relapse. Whereas Glutathione for Lyme disease recovery is often on a weekly or biweekly basis with IV Alpha Lipoic Acid which also improves nerve Glutathione status. What can IV glutathione be used for? Most commonly our Naturopaths suggest IV Glutathione for MS, Skin Brightening and Lightening, Detoxification and Parkinson's and Lyme.
Are they any side-effects to IV Glutathione? Surprisingly, despite using aggressive dosing occasionally Glutathione is extremely well tolerated in an IV context. Our Naturopaths have administered IV Glutathione in high doses (1000 to 8000mg) for a decade with almost no side effects. If IV Glutathione is administered too rapidly it can cause brief shortness of breath and a slight head pressure or if it's administered on a chronic basis it can deplete molybdenum stores and reduce tolerance to Glutathione. Glutathione and Hyperbaric Oxygen
Vitamin E is believed to protect against oxygen toxicity by counteracting the oxygen free radicals . A dose of 400 mg daily can be given to patients scheduled for Hyperbaric Therapy starting 2 days before the therapy Regardless of the minimal effect of HBOT on Glutathione Peroxidase, we consider a potential additive action when IV Glutathione is administered after Hyperbaric treatment with regards to neurological repair as we have published data available for treatments like Alpha Lipoic Acid that can hasten neurological recovery in conditions like diabetic neuropathy, but the area certainly requires more study. Curious About IV Glutathione?Call us (780) 757-8378 |
||