IV Vitamin C Therapy in Edmonton
Our Naturopaths offer Vitamin C IV Therapy in Edmonton.
IV Vitamin C is one of the top IV Therapies our Naturopaths offer Edmonton.
IV Vitamin C has a wealth of data supporting its use in a wide range of health conditions.
For immunity IV Vitamin C is often given with Zinc, Selenium, and Hydrochloric Acid.
For cosmetics, Vitamin C is usually given back to back with Glutathione.
With cancer, IV Vitamin C is usually given with supportive minerals in dramatic doses.
IV Vitamin C dosing varies widely, our Naturopaths are usually using between 5 grams and 125 grams per infusion.
Intravenous vitamin C can reach concentrations up to 30 to 70 times higher than the same oral dose taken orally.
IV Vitamin C
Intravenous vitamin C bypasses intestinal absorption and the associated transport mechanisms which saturate as the dose of Vitamin C increases orally.
In one study even with administration of a small dose of 1.25 grams of vitamin C intravenously reached 885 micromoles/L in the blood versus 135 micromoles/L orally.
Although our Naturopathic Doctors don't treat sepsis or myocarditis the following examples simply illustrate the role of IV Vitamin C in infections and that the regular medical community is making strides in accepting this as a therapy.
IVC and Sepsis: IV Vitamin C reduces the number of hospital deaths among patients with sepsis.
One study with more than 160 patients admitted to ICU for sepsis-induced acute respiratory failure with 50 mg/kg of IV Vitamin C every six hours for 4 days. 28 days after the beginning of the study, about 46 percent of the patients in the placebo group died, compared to less than 30 percent in the IV vitamin C-treated group
and more ventilator-free days, transfer from ICU at a higher rate, and had an average increase of seven hospital-free days compared to the placebo group.
Another study looked at 47 sepsis patients with 24 grams Vitamin C per day for four days along with a steroid and B1 versus the control group who received the standard of care. About 40 percent of the patients in the control group died, but only 8 percent of the patients in the IVC group died and has improved organ function.
Viral Myocarditis: An analysis looked at data from eight studies with more than 420 children who were given conventional treatment and IV vitamin C. A control group with more than 360 children received conventional therapy alone.Overall, standard therapy with IV vitamin C decreased all measured cardiac related enzymes, compared to conventional therapy alone .
COVID-19: Interestingly, data emerged from China in March of 2019 regarding IV Vitamin C and COVID-19. One group stated that they treated ~50 cases of moderate to severe Covid-19 with high dose IVC (dosing was in the range of 10,000 mg - 20,000 mg a day for 7-10 days, with 10,000 mg for moderate cases and 20,000 for more severe cases). The group stated that ll patients who received IV Vitamin C improved and there was no mortality. Compared to the average 30-day hospital stay the IVC patients had a 3-5 days shorter hospital stay.
Herpes Zoster (shingles): In a study of 41 patients with postherpetic neuralgia (nerve pain that can develop after a shingles rash) who received three infusions of 2.5 grams of IV vitamin C or a placebo over a period of five days, those who received the infusions reported having less spontaneous postherpetic neuralgia pain compared to the control group.
In our experience with our Edmonton patients, IV Vitamin C needs to be administered with high dose B1 and B12 as soon as a shingles rash develops to hasten healing and reduce likelihood of postherpetic neuralgia as is demonstrated in published case reports.
Reperfusion injury: One study with 560 patients where one group received 3 grams of IV vitamin C within six hours of coronary intervention, and the other received saline. Markers of heart injury were decreased in the IV vitamin C group, compared to the controls, suggesting that intravenous vitamin C is associated with less heart injury.
In 2018, a review by Bazzan looked at 86 cancer patients received doses of IV Vitamin C ranging from 50g to 150g at Thomas Jefferson University Hospital over a 7-year period. 32 patients received only IV Vitamin C for cancer management and 54 patients received IV Vitamin C concurrently with chemotherapy (paclitaxel, carboplatin, sorafenib, irinotecan, and gemcitabine).
Improvements in fatigue, pain, and mood with IV Vitamin C were reported
Another 2018 review by Nauman looked at 385 cancer patients in 23 trials using Intravenous vitamin C. It was concluded that IV Vitamin C was safe in nearly all patient populations, alone and in combination with chemotherapies
IV Vitamin C Safety
IV Vitamin C has been administered in doses as high as 200 g without adverse consequences and a study at McGill found no toxicity at doses of up to 125g of IV Vitamin C. Up to 1500mg/kg three times weekly for cancer has been tolerated and considered safe.
Prior to treatment with high doses (>30g), our Naturopathic doctors run a test called a G6PD Screen (glucose-6-phosphate dehydrogenase) and do measurements of renal function.
Vitamin C levels from IV infusion are cytotoxic to select cancer cell lines but not to normal cells as normal cells have more catalase enzyme that dismutates hydrogen peroxide generated from the Vitamin C.
IV Vitamin C Dosing
For Cancer our Naturopathic doctors often administer up to 1.5 g/kg up to three times weekly, as this dose appears to be safe and free of toxicity and sustains plasma ascorbic acid concentrations >10 mmol/l for >4 h in patients with normal renal function. In part, because apoptotic cell death occurs in many cancer cell lines exposed to ascorbate concentrations >5 mmol/l for <1 h.
For infections, immunity and longevity our Naturopaths usually dose IV Vitamin C between 5 to 35 grams.
IV Vitamin C and Infections
Our Naturopathic Doctors use low dose IV Vitamin C (5-15grams) primarily for acute infections like colds and flus.
Chronic infections such as Epstein-Barr Virus (EBV) or HHV-6 may require doses between 15 and 35grams (moderate dose IVC). Results on 178 patients from the Riordan Clinic with acute Epstein-Barr were treated with 7.5 to 50g of Vitamin C IV showed a reduction in antibody levels an indication that Vitamin C can affect viral infection and replication.
IV Vitamin C and Hyperbaric Oxygen
The level of tissue oxygenation is considered one of the most important factors in the anticancer activity of high dose IV vitamin C. The presence of sufficient oxygen is a requisite for production of hydrogen peroxide from the conversion of ascorbic acid to dehydroascorbic acid.
One group has published "We propose the utilization of hyperbaric oxygen immediately after IV vitamin C therapy to increase its effectiveness as an anticancer agent, in order to increase the formation of hydrogen peroxide, and therefore enhance the anticancer effect of IV vitamin C."
Dominic P. D’Agostino is a PhD researcher that has published a lot of data on ketogenic diets and cancer as well as hyperbaric medicine and cancer.
He conducted experiments with his group with regards to IV Vitamin C (Ascorbic Acid or "AA") and Hyperbaric Oxygen Therapy. They set out to "evaluate AA-induced oxidative stress, and to investigate AA’s synergy with
VM-M3 Cells were used: highly metastatic cells derived from a spontaneous brain tumor in a VM/Dk inbred mouse. Cells were treated with a less than cytotoxic concentration of AA (<0.5mM) and one session of HBOT (100% O2 for 60 minutes at 2.5 ATA). <0.5mM was used as doses higher than this are already cytotoxic on their own.
Co-treatment with HBOT and 0.3mM AA significantly increased cytotoxicity compared to all other treatments.
• Low dose Vitamin C (under 25 grams) pair with HBOT from 1.3 to 2.5 ATA
• High dose strategies (over 25 grams) should be paired with 1.3 to 1.5 ATA.
Questions about IV Vitamin C?