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Home/Investigated Indications Print This Page


Hyperbaric Oxygen Investigated Conditions

Stroke, MS, Lyme & TBI 


TruMed will be offering Edmonton Hyperbaric Oxygen Therapy starting in early 2021.  


The Naturopaths at TruMed have put the magnifying glass over the research of a few specific health conditions and Hyperbaric Oxygen Treatment. This review page is for informational purposes only. 


Our Naturopathic doctors offer Edmonton Hyperbaric Oxygen, IV Therapy, Functional Medicine and Orthomolecular Nutrition. Alternative medicine has options to improve outcomes in chronic stroke patients.



A wealth of data exists with regards to Hyperbaric Oxygen and a range of health conditions. In particular, Stroke, MS, TBI and Lyme Disease are areas that our Naturopathic doctors take interest in. Each area discussed has its own, larger section. Each condition also has substantial data regarding Naturopathic approaches to treatment.


Stroke 

An ischemic stroke occurs when there is a block to an artery to the brain and consequently the transport of oxygen and glucose causes subsequent neurological dysfunction that lasts longer than 24 hours. 


Select Hyperbaric Studies in Stroke: 


The reported cases using Hyperbaric Oxygen in stroke is well over 1000 with an encouraging rate of improvement between 40–100 %. This degree of improvement which is higher than the expected natural rate of recovery (Jain 2017). 


Select Stroke Hyperbaric Studies 

Holbach and Wassman (1979) 131 patients - 1. 5 ATA, 1 h/day Improvement in 80% of acute and 43% of chronic cases
Nagakawa et al. (1982) 22 patients, 2 ATA, 1 h/day, 12 treatments

Excellent recovery in 6, 7 moderate, slight in 6, 3 no response

Hao and Yu (1987) 978, 798 were stroke patients, 20–30 sessions but pressure not given 

Improvement in 82.3 % of cases


The "Klausenbach Study" was carried out by Jain in the late 80's, looked at fifty chronic stroke patients (up to 5 years post incident).


Daily Hyperbaric oxygen therapy was given for 45 min at 1.5 ATA for 6 weeks with simultaneous physical therapy. 


All 50 patients in the "Klausenbach Study" showed positive improvement. 


Jain's Klausenbach Study

Mental function 35 patients

86% improved 

Gait 24 patients

41% improved

Motor power 50 patients

50% improved


Our general Naturopathic IV approach would be to provide nourishment to the brain both orally and intravenously. IV Phospholipids, IV Glutathione and IV B-Vitamins with Glutathione support nutrients (Zinc, Selenium, Vitamin C) would be key treatments to be done 1-3 times weekly pre or post hyperbaric treatment. Orally our Naturopaths adore Citicholine: In a one year study 199 patients took Citicholine and cognitive functions improved 6 and 12 months after stroke. 


For more information on Hyperbaric treatment of Stroke click here.



MS


Hyperbaric Medicine in the treatment of MS has promise not only to alter the course of the disease but to help repair damaged areas. Initially, HBO therapy was shown to ameliorate symptoms in Experimental Allergic Encephalomyelitis (EAE) the animal model of multiple sclerosis. Stem Cells release from Hyperbaric treatment is one mechanism that can contribute to the repair of areas of damage. 


With regards to the course of disease Pallota (1986) followed 22 MS patients after they had an initial course of 20 HBO treatments, and 11 patients had continued treatment every 3 weeks. These patients were followed over 8 years.


The frequency of relapses decreased dramatically in the long term treatment group whereas they increased in the group which received the initial treatment. 


UK MS Data


In the United Kingdom a charity called "The MS National Therapy Centres" installed Hyperbaric facilities across the UK and has treated over 25,000 MS patients


The cases of 703 MS patients who were followed in detail has been published. 

 

Five daily treatments of 1 hour were given at 1.25 or 1.5 ATA. and if two or more symptoms improved, a course of 20 treatments in 4 weeks was completed at the "best" pressure. Otherwise, the pressure was raised in weekly increments of 0.25 ATA until a response was obtained or five treatments at 2.0 ATA had no effect

 

After twenty treatments, 70 % of patients obtained relief of two or more symptoms.


An analysis suggested that one treatment every 2 weeks was required to retard the progression of relapsing/remitting state where as once weekly was even more effective looking at data of patients after 14 years. 

Improvement 20 treatments

Walking 

638 patients

77% improved

Fatigue

567 patients

70% improved

Bladder

523 patients

68% improved

Balance

562 patients

59% improved


Naturopathic IV Treatment can be helpful for our Edmonton MS patients with regards to energy, mood, spasticity, acute inflammation and in some cases walking. IV Glutathione is our best option for acute inflammation.


NAD+ IV is a newer promising option for energy in MS but is thought to be helpful for preventing neurodegeneration in chronic MS. 


Low Dose Lithium is an interesting Naturopathic oral treatment option as it is one avenue to activate myelin producing oligodendrocytes (stimulate differentiation of Oligodendrocyte precursor cells) as well as inhibit inflammatory microglia. 


For more information on Hyperbaric treatment of MS click here.


TBI


Up to 90% of the Traumatic Brain Injuries are classified as mild TBI (mTBI) or concussion. 


Post concussion syndrome (PCS) is a set of symptoms in most mTBI patients which includes headache, dizziness, psychiatric symptoms, and cognitive impairment. These symptoms may continue for weeks or months, and last for over six months in 25%. 


Increased tissue oxygenation, Reduced inflammation, Decreased apoptosis and increased blood vessel formation are all suggested mechanisms by which Hyperbaric Oxygen can help in TBI.


In a study by Harch in 2012, Hyperbaric Oxygen was used in 16 war veterans with blast-induced TBI received 40 HBO sessions (1.5 ATA for 1 hour) in 30 days


Twelve of 15 subjects (80%) reported improvement in a majority of their symptoms on their prioritized symptom list after HBOT.


Harch TBI results

Cognition 93% of patients improved

14/15 patients 

Short Term Memory 92% of patients improved 

11/12 patients

Headache 87% of patients improved 13/15 patients


Boussi-Gross et al. 2013 conducted trial of HBOT on 56 mTBI patients up to 5 years after injury with 40 60 minute 1.5 ATA sessions.

 

A significant improvement was observed in the treated group after HBOT in all cognitive measures: Information Processing Speed, Attention, Memory, and Executive Functions. 


SPECT scans showed HBOT led to reactivation of neuronal activity

Boussi-Gross 2013

Boussi Gross mild TBI and hyperbaric oxygen

Hyperbaric & mTBI




Our TBI IV Therapy will be a rendition of the following: 


Anderson Standard HBOT + IV Head Trauma Protocol:

 

IV three-part formula:
• Vitamin-Mineral Amino Acid Formula
• 1 to 3 grams Glutathione
• Lipoic Acid Mineral Complex IV
• +/-IV Phospholipids (in those with chronic injuries / psychiatric overlay)


Our Naturopathic doctors have had a reasonable amount of success in mTBI  using the first two suggestions - namely the Vitamin, Mineral Amino acids IV Formula prior to 2-4 grams of Glutathione. We believe in general there is probably a slight preference to try and administer an IV prior to Hyperbaric Treatment however tissue oxygenation persists for hours after Hyperbaric Intervention so IV treatments given after can benefit from this as well.


For more information on Hyperbaric treatment of TBI click here.


Lyme Disease


Lyme disease, is a bacterial infection caused by Borrelia burgdorferi from infected ticks.  Borrelia species can infect any tissue or organ system but most commonly we see neurological issues, cardiac and joint problems. 


Hyperbaric oxygen is thought to have the dual role of being inhibitory towards bacteria but at the same time restorative to damaged body systems especially the nervous system. 



Chronic Lyme Symptoms: 

Fatigue

 Dizziness or vertigo 

Memory loss or cognitive impairment 

Sleep disturbances 

Numbness or tingling of extremities 

Sensory distortion of the skin

and many others


The famous "Texas A&M University" program in the early 1990s treated Chronic Lyme Disease patients with up to 40, 60 minute 2.36 ATA HBO sessions. 

 

Improvement or resolution of Chronic Lyme symptoms was seen in 37/38 patients within 3 weeks of completing treatment and these effects were sustained in approximately 70% of those patients for up to 6 years. 


Naturopaths at TruMed work with IV Therapy for our Edmonton Lyme patients: IV Alpha Lipoic Acid, IV Glutathione and IV Phospholipids based largely off treatment suggestions from Dr. Richard Horowitz M.D. These three IVs are often "stacked," that is, given back to back.  


IV therapy with Alpha Lipoic Acid and IV Glutathione can deal with inflammation induced damage of cell membranes, mitochondria, and nerves. 


IV Therapy with Phospholipids, can be helpful for mitochondrial restoration and neuronal restoration.


Our Naturopaths work with alkaline, anti-inflammatory diets and to a lesser extent we work with Cowden, Zhang, Buhner, Byron White anti-Lyme protocols or can refer for anti-biotic protocols. 


For more information on Hyperbaric treatment of Lyme Disease click here. 


Curious about Hyperbaric Treatment?

(780) 757-8378



TruMed

Hyperbaric Oxygen
& IV Therapy

Naturopaths Edmonton 

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Mon - Fri

Hours: 10am - 5pm

Make it TruMed.


Call 780-757-8378

Email info@trumed.ca


#4 11630 119 st 

Edmonton, Alberta

T5G 2X7

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